Revolutionær nukleinsyreekstraktionsteknologi: Shanghai Lingjun Bio 220011 magnetiske perler føre en ny æra af videnskabelig forskning effektivitet

Den videnskabelige forsknings fremskridt begynder ofte med små innovationer i eksperimentelle værktøjer. I utallige laboratorier, en tavs teknologisk revolution finder sted.

Inden for genomik, molekylær diagnostik, and biomedical research, nucleic acid extraction and purification are fundamental steps in almost every experiment. Traditional methods are time-consuming and labor-intensive, with low recovery rates and difficult to guarantee purity, especially when dealing with trace or trace samples.

De 220011 fragment sorting magnetic beads launched by Shanghai Lingjun Biotechnology Co., Ltd. are changing this status quo, becoming a new choice for scientific researchers at home and abroad with its excellent performance and reliability.

Technological innovation

220011 magnetic beads are made of superparamagnetic silica matrix with Si-OH active groups, with an average particle size of 500 nm, excellent suspension (Figur 1), and a semi-sedimentation time of more than 1 hour.

The magnetic saturation strength of this magnetic bead reaches 65±5 emu/g, which has strong magnetic responsiveness and can complete the separation operation in a short time, greatly improving the experimental efficiency.

Superior performance

The most striking feature of 220011 magnetic beads is their recovery rate of over 95%, which can maintain this high level of recovery even when treating trace DNA samples up to 20 ng/μL.

This means unprecedented recovery efficiency and reliability of experimental results for those experiments where samples are precious and rare. Whether it’s clinical or archaeological samples, researchers can now conduct experiments with greater confidence.

The magnetic beads offer excellent suspension properties and adsorption capabilities, allowing them to be evenly dispersed in solution, maximizing contact with nucleic acid molecules.

Widely used

220011 fragment sorting magnetic beads are suitable for nucleic acid extraction of a variety of sample types, including but not limited to: the extraction and purification of genomic DNA from whole blood, animal tissues, plantevæv, bakterie, plasmids, osv., as well as the separation and purification of viral DNA/RNA and small fragment DNA/RNA.

In particular, it excels in the extraction of serum/plasma cell-free DNA/RNA fragments, meeting the current urgent needs in the field of liquid biopsy and non-invasive diagnostics.

Experimental case: 100bp exogenous nucleic acid fragments were added to the serum, and the simulation experiment was carried out, and the sample was extracted and then qPCR was performed.

Resultatanalyse：It shows that the reagent system extracts nucleic acids with good purity and reproducibility.

The electrophoresis results were as follows, sample starting volume: 200 μL, 80 μL elution, 6 μL top sample electrophoresis, agarose gel concentration of 1%, 120 V, electrophoresis for 30 min.

Resultatanalyse：As can be seen from the above figure, the experimental results are reproducible and can meet the experimental requirements of downstream qPCR, ddPCR and high-throughput sequencing.

Easy to operate

Compared with traditional methods, the operation process of 220011 magnetic beads is simpler and does not require the use of toxic reagents such as phenol/chloroform, greatly reducing the health risks of experimenters.

This product is suitable for automated workstations and automatic nucleic acid extraction instruments, realizing one-click automatic extraction, reducing human operation errors and improving the repeatability and consistency of experimental results.

Quality assurance

As a national high-tech enterprise and a specialized and special new enterprise in Shanghai, Shanghai Lingjun Biotechnology Co., Ltd. has passed the ISO9001:2015 quality management system certification.

The company strictly controls the production process to ensure that the stability of the magnetic beads is good and there is no significant difference, which provides a reliable guarantee for scientific research work.

Leverandør

Shanghai Lingjun Biotechnology Co., Ltd.blev etableret i 2016 som er en professionel producent af biomagnetiske materialer og nukleinsyreekstraktionsreagenser.

Vi har stor erfaring med udvinding og oprensning af nukleinsyre, proteinoprensning, celleadskillelse, kemiluminescens, og andre tekniske områder.

Vores produkter er meget udbredt inden for mange områder, såsom medicinsk test, genetisk testning, universitetsforskning, genetisk avl, og så videre. Vi leverer ikke kun produkter, men kan også påtage os OEM, ODM, og andre behov. Hvis du har et relateret behov, er du velkommen til at kontakte os .