Professional Manufacturer of Biomagnetic Beads
LnjnBio 160014 magnetic beads feature a superparamagnetic Fe3O4 core-SiO2shell structure. Through precise control of the silanization modification process, a high-density hydroxyl functional group is constructed on the bead surface. This unique structure enables rapid response to external magnetic fields (magnetic response time < 10 seconds) and negligible residual magnetism after demagnetization (coercivity < 5 Oe), ensuring excellent dispersion and reusability. With nucleic acid recovery rates exceeding 90% and a sedimentation half-life of 16–30 minutes, these beads deliver superior suspension stability and operational convenience, making them ideal even for high-throughput sample processing.
Product Specifications & Performance
| 160014 | |
| Active group | Si-OH |
| Magnetic bead matrix | Superparamagnetic silica |
| Mean particle diameter | 2µm |
| Value of saturated magnetic | 75±5emu/g |
60014 Magnetic Beads are primarily suitable for the extraction and purification of genomic DNA from moderate to large quantities of plant tissue, animal tissue, and whole blood. They are particularly well-suited for whole blood, peripheral blood, genomic DNA extraction, and co-extraction of DNA/RNA, offering a high binding capacity. Taking 20 ng/µl target DNA as an example, the beads achieve a recovery rate of approximately 90% or higher (as shown in Table 1).
Table 1: Batch stabilisation and adsorption properties
| Sample | 200 µl frozen anticoagulated porcine whole blood | 20ng/µl DNA | ||
| 260/280 | 260/230 | Conc.(ng/µl) | Recovery | |
| 160014 batch 1 | 1.940 | 2.113 | 139.30 | 94.81% |
| 1.941 | 2.098 | 140.15 | ||
| 1.935 | 2.104 | 139.20 | ||
| Avg | 1.94 | 2.11 | 139.55 | |
| 160014 batch 2 | 1.904 | 2.068 | 123.15 | 93.03% |
| 1.941 | 1.930 | 102.20 | ||
| 1.952 | 2.012 | 96.55 | ||
| Avg | 1.93 | 2.00 | 107.30 | |
Customer Feedback
A customer used our model 160014 to simultaneously extract two types of samples, with one sample undergoing five replicates. The measured concentration results are as follows:
| Sample | A260/A280 | A260/A230 | Conc. (ng/uL) |
| DZ 1 | 2.063 | 1.756 | 662.193 |
| DZ 2 | 2.072 | 1.644 | 767.457 |
| DZ 3 | 2.085 | 1.636 | 804.403 |
| DZ 4 | 2.096 | 1.67 | 810.99 |
| DZ 5 | 2.102 | 1.65 | 797.154 |
| DJ 1 | 2.091 | 1.676 | 830.792 |
| DJ 2 | 2.106 | 1.651 | 1173.922 |
| DJ 3 | 2.076 | 1.67 | 823.917 |
| DJ 4 | 2.066 | 1.697 | 838.414 |
| DJ 5 | 2.084 | 1.68 | 855.57 |
Gel electropherogram
From the above results, it can be seen that the 160014 magnetic beads have excellent performance in extracting nucleic acids and the extracted fragments are complete and clear, which is especially suitable for on-line batch extraction.
Experimental Cases
Case 1: Use of 160024 handheld different plant seed germinal parts
| No. | Sample | Sample intake | 260/280 | 260/230 | Conc. (ng/ul) |
| 1 | Red beans | 10 mg | 1.988 | 1.794 | 167.8 |
| 2 | Soybead | 1.996 | 2.051 | 549.9 | |
| 3 | Peanut | 1.957 | 1.507 | 154.85 | |
| 4 | Black rice | 1.956 | 1.644 | 133.05 | |
| 5 | Japonica rice | 1.95 | 1.898 | 96.4 | |
| 6 | Maize | 1.84 | 1.268 | 161.35 |
Gel electropherogram
From the above experimental results, it can be verified that for the manually extracted plant seed germ samples, the genomic fragments recovered by 160014 magnetic beads were of good purity (A260/A280>1.8, 260/230>1.2), and the fragments were complete.
Case 2: Effect of DNA extraction on 10-15 mg of polysaccharide polyphenol plant genome
| No. | Sample | Sample intake（mg） | A260/A280 | A260/A230 | Conc.(ng/µL) | Yield（µg） |
| 1 | Dandelion fresh leaves | 15mg | 1.84 | 1.698 | 44.4 | 4.44 |
| 2 | Perilla fresh leaves | 15mg | 1.745 | 1.379 | 110.1 | 11.01 |
| 3 | Ospecios fresh leaves | 10mg | 1.755 | 1.463 | 55.7 | 5.57 |
| 4 | Dichondra fresh leaves | 15mg | 1.838 | 1.661 | 64.65 | 6.47 |
| 5 | Desmodium fresh leaves | 15mg | 1.843 | 1.777 | 89.85 | 8.99 |
| 6 | Alternanthera philoxeroides fresh leaves | 15mg | 1.855 | 1.79 | 39.65 | 3.97 |
| 7 | Plantain fresh leaves | 15mg | 1.872 | 1.969 | 104.2 | 10.42 |
Gel electropherogram
From the above experimental results, it can be verified that the 160014 magnetic beads have high recovery of genomic fragments of 10-15mg polysaccharide and polyphenol plant samples with a yield of more than 15 µg, and good purity (A260/A280>1.75, 260/230>1.4), and complete genomic fragments.
Leader Bio 160014 silica-based magnetic beads are becoming a new benchmark in the field of nucleic acid extraction due to their high recovery rate, excellent suspension and strong magnetic properties.
The company not only provides high-quality products, but also develops a variety of magnetic bead-based nucleic acid extraction and purification reagents, which can isolate and purify high-quality genomic DNA/RNA from a wide range of samples such as blood, serum/plasma, saliva, bacteria, fungi, swabs, faeces, animal and plant tissues, and so on.
Whether for basic scientific research or clinical testing applications, this product can provide reliable technical support and excellent experimental results.
Ltd. will continue to provide more high-quality products and services for the life science field with the impetus of technological innovation, helping researchers to explore the mysteries of life and promoting the development of biomedicine.
Supplier
Shanghai Lingjun Biotechnology Co., Ltd. was established in 2016 which is a professional manufacturer of biomagnetic materials and nucleic acid extraction reagents.
We have rich experience in nucleic acid extraction and purification, protein purification, cell separation, chemiluminescence, and other technical fields.
Our products are widely used in many fields, such as medical testing, genetic testing, university research, genetic breeding, and so on. We not only provide products but also can undertake OEM, ODM, and other needs. If you have a related need, please feel free to contact us at sales01@lingjunbio.com.
