Toepassing van magnetische kralenmethode voor nucleïnezuurextractie in dierlijke weefsels bij de detectie van huisdieren

In de wereld van vandaag, waar huisdieren integrale leden van gezinnen zijn geworden, hun gezondheid is een topprioriteit voor elke eigenaar. Echter, huisdierziekten vertonen vaak subtiele symptomen, while traditional detection methods frequently suffer from issues like time-consuming processes and low sensitivity. How can we swiftly and accurately identify disease indicators? The Magnetic Beads Method Animal Tissue DNA/RNA Extraction Kit delivers a groundbreaking solution through innovative technology, revolutionizing pet health monitoring!

Why magnetic bead method for nucleic acid extraction?

This technology utilizes ultra-paramagnetic magnetic beads for specific nucleic acid adsorption, enabling efficient extraction of DNA/RNA from pet tissues (including skin, tumors, and internal organs). It precisely captures even trace pathogens, providing high-purity templates for molecular diagnostics in canine distemper, feline panleukopenia, and pet tumors, with detection sensitivity increased by over 50%.

Eliminating toxic reagents like phenol/chloroform, the process completes in 15 minutes with 70% simplified procedures. Compatible with automated equipment, it is ideal for pet hospitals and testing institutions to rapidly conduct high-throughput screening, significantly boosting detection efficiency.

The proprietary optimized buffer system effectively resists interference from inhibitors in pet tissues, ensuring excellent nucleic acid integrity and full compatibility with downstream PCR, whole-genome sequencing (WGS), and next-generation sequencing (NGS) methods, guaranteeing zero-error test results.

Full coverage of application scenarios

• Pet Disease Diagnosis: Viral/bacterial infection detection: Nucleic acid testing for pathogens such as canine distemper virus (CDV), feline panleuropoiesis virus (FPV), and rabies. Rapid diagnosis is achieved through PCR or sequencing analysis of nucleic acids extracted from tissues (blood, lymph nodes, intestinal tissue) of infected pets. Parasite detection: DNA/RNA extraction for parasites like Toxoplasma gondii and Babesia spp. for molecular identification and drug resistance analysis.
• Genetic Disease Screening: Gene mutation analysis: Genetic sequencing or SNP profiling using DNA extracted from tissues or oral swabs for inherited diseases in dogs and cats (e.g., polycystic kidney disease, progressive retinal atrophy).
• Tumor Molecular Diagnosis: Cancer-related gene testing: Detection of mutated genes (e.g., TP53, BRAF) from tumor tissues to assist in personalized treatment plans.
• Pet Health Management: Gut microbiome analysis: Microbial DNA extraction from fecal samples to study the relationship between gut flora and pet health (e.g., obesity, allergies).
• Forensic & Paternity Testing: Identification or analysis of pet identity through DNA extraction from oral mucosa or hair roots.

Future Development Directions: Portability

 Develop compact extraction devices compatible with point-of-care testing (POCT) systems in veterinary clinics. Multi-plex detection: Integrate microfluidic technology to achieve integrated nucleic acid extraction and multiplex PCR analysis. The application of magnetic bead-based kits in pet diagnostics has significantly enhanced diagnostic efficiency and accuracy. With the expansion of the pet healthcare market, demand for these solutions is expected to grow substantially.

Leverancier

Shanghai Lingjun Biotechnologie Co., Ltd.werd opgericht in 2016 dat een professionele fabrikant is van biomagnetische materialen en reagentia voor nucleïnezuurextractie.

We hebben een rijke ervaring in de extractie en zuivering van nucleïnezuren, eiwit zuivering, cel scheiding, chemiluminescentie, en andere technische gebieden.

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