Lnjnbio® DNA Fragment Recycling Beads FR0012

This product is designed to recover nucleic acid fragments of different molecular weights in specific ratios of magnetic bead suspensions using nano-magnetic beads with unique separating effects in conjunction with an optimised buffer system. The product is suitable for the recovery, isolation or purification of DNA within a specific length range greater than 100bp. The whole operation process is convenient and fast, and the sorting product is suitable for the length sorting of DNA during the construction of high-throughput sequencing libraries. By adjusting the dosage of the product and by unilateral or bilateral (once or twice) separation and purification, the isolation and purification of DNA of different length ranges can be achieved.

Specifications

50 mL/500 mL/1000 mL

Characteristics

• This product has strong specificity and high DNA binding capacity. The product has fast DNA binding speed and high binding capacity, and nucleic acid fragments of different sizes can be separated and purified quickly. Moreover, the small particle size of magnetic beads is not easy to produce non-specific adsorption, which can quickly and effectively remove unadulterated dNTP, primers, primer dimers, salts and other contaminants.
• The product is highly compatible. The product is not only suitable for manual operation of a small number of samples, but also suitable for high-throughput automated operating system.
• Convenient and efficient sorting length range. The product can be adjusted by adjusting the amount of magnetic beads and thus adjusting the range of DNA sorting length to meet the needs of different experiments. The results are consistent from batch to batch. The range of sorted fragments is consistent with the experimental preset, and the experimental results can be predicted.
• The product is easy to operate. The product adopts magnetic separation without centrifugation, which helps to retain the integrity of nucleic acids and has a high recovery rate of DNA fragment purification.
• This product is safe and environmentally friendly. Compared with traditional DNA recovery methods, it avoids the use of organic solvents such as phenol and chloroform, which is safer.

Application

NGS Library Preparation and Refinement
This represents its primary application, crucial for purifying DNA at various stages of library construction, eliminating impurities (such as primer dimers), and most importantly, precisely selecting DNA fragments of specific lengths to ensure sequencing quality.

Routine PCR Product Purification
Enables the rapid purification of PCR products by removing reaction components like primers, primer dimers, enzymes, and dNTPs, yielding high-purity DNA for downstream applications (e.g., cloning, sequencing).

Replacement for Agarose Gel Extraction
By adjusting the bead-to-sample ratio, target DNA fragments of specific sizes can be isolated directly from a mixture. This circumvents the tedious gel excision step, offering a faster, more efficient method that avoids UV-induced DNA damage.

Selective Enrichment of Specific Small Fragments
Used to selectively capture short DNA fragments. A key example is in non-invasive prenatal diagnostics and liquid biopsies, where it efficiently isolates vital circulating free DNA (cfDNA) from blood samples while removing longer background genomic DNA.

Storage & Expiry date

Store at 2-8°C, valid date is 1 years.Avoid freezing!

Note

• Resuspend the beads thoroughly for a few minutes before usage.
• Freezing, drying, or centrifuging Lnjnbio® Magnetic Beads may result in irreversible aggregation and loss of binding activity.

Supplier Introduction

Shanghai Lingjun Biotechnology Co., Ltd. was established in 2016 and is a professional manufacturer of biomagnetic materials and nucleic acid extraction kit.

We have rich experience in nucleic acid extraction and purification, protein purification, cell separation, chemiluminescence and other technical fields.

Our products are widely used in many fields, such as medical testing, genetic testing, university research, genetic breeding, and so on. We not only provide products but can also undertake OEM, ODM, and other needs. If you have related needs, please feel free to contact us at sales01@lingjunbio.com.