Revolutionary nucleic acid extraction technology: Shanghai Lingjun Bio 220011 magnetic beads lead a new era of scientific research efficiency

The progress of scientific research often begins with small innovations in experimental tools. In countless laboratories, a silent technological revolution is taking place.

In the fields of genomics, molecular diagnostics, and biomedical research, nucleic acid extraction and purification are fundamental steps in almost every experiment. Traditional methods are time-consuming and labor-intensive, with low recovery rates and difficult to guarantee purity, especially when dealing with trace or trace samples.

The 220011 fragment sorting magnetic beads launched by Shanghai Lingjun Biotechnology Co., Ltd. are changing this status quo, becoming a new choice for scientific researchers at home and abroad with its excellent performance and reliability.

Technological innovation

220011 magnetic beads are made of superparamagnetic silica matrix with Si-OH active groups, with an average particle size of 500 nm, excellent suspension (Figure 1), and a semi-sedimentation time of more than 1 hour.

The magnetic saturation strength of this magnetic bead reaches 65±5 emu/g, which has strong magnetic responsiveness and can complete the separation operation in a short time, greatly improving the experimental efficiency.

Superior performance

The most striking feature of 220011 magnetic beads is their recovery rate of over 95%, which can maintain this high level of recovery even when treating trace DNA samples up to 20 ng/μL.

This means unprecedented recovery efficiency and reliability of experimental results for those experiments where samples are precious and rare. Whether it’s clinical or archaeological samples, researchers can now conduct experiments with greater confidence.

The magnetic beads offer excellent suspension properties and adsorption capabilities, allowing them to be evenly dispersed in solution, maximizing contact with nucleic acid molecules.

Widely used

220011 fragment sorting magnetic beads are suitable for nucleic acid extraction of a variety of sample types, including but not limited to: the extraction and purification of genomic DNA from whole blood, animal tissues, plant tissues, bacteria, plasmids, etc., as well as the separation and purification of viral DNA/RNA and small fragment DNA/RNA.

In particular, it excels in the extraction of serum/plasma cell-free DNA/RNA fragments, meeting the current urgent needs in the field of liquid biopsy and non-invasive diagnostics.

Experimental case: 100bp exogenous nucleic acid fragments were added to the serum, and the simulation experiment was carried out, and the sample was extracted and then qPCR was performed.

Result analysis：It shows that the reagent system extracts nucleic acids with good purity and reproducibility.

The electrophoresis results were as follows, sample starting volume: 200 μL, 80 μL elution, 6 μL top sample electrophoresis, agarose gel concentration of 1%, 120 V, electrophoresis for 30 min.

Result analysis：As can be seen from the above figure, the experimental results are reproducible and can meet the experimental requirements of downstream qPCR, ddPCR and high-throughput sequencing.

Easy to operate

Compared with traditional methods, the operation process of 220011 magnetic beads is simpler and does not require the use of toxic reagents such as phenol/chloroform, greatly reducing the health risks of experimenters.

This product is suitable for automated workstations and automatic nucleic acid extraction instruments, realizing one-click automatic extraction, reducing human operation errors and improving the repeatability and consistency of experimental results.

Quality assurance

As a national high-tech enterprise and a specialized and special new enterprise in Shanghai, Shanghai Lingjun Biotechnology Co., Ltd. has passed the ISO9001:2015 quality management system certification.

The company strictly controls the production process to ensure that the stability of the magnetic beads is good and there is no significant difference, which provides a reliable guarantee for scientific research work.

Supplier

Shanghai Lingjun Biotechnology Co., Ltd. was established in 2016 which is a professional manufacturer of biomagnetic materials and nucleic acid extraction reagents.

We have rich experience in nucleic acid extraction and purification, protein purification, cell separation, chemiluminescence, and other technical fields.

Our products are widely used in many fields, such as medical testing, genetic testing, university research, genetic breeding, and so on. We not only provide products but also can undertake OEM, ODM, and other needs. If you have a related need, please feel free to contact us .