Comment l’extraction d’acide nucléique par billes magnétiques accélère les laboratoires?

Avant-propos

New regulations in Chongqing will take effect in December—when blood is drawn during an outpatient visit, an HIV test will be conducted by default unless you explicitly refuse it. Sichuan, Guangxi, and other regions are also simultaneously implementing a policy of “testing every blood sample.”

Qu'est-ce que cela signifie? The demand for batch testing in clinical laboratories is shifting from “targeted testing for a small number of people” to “comprehensive coverage of all outpatient patients across the hospital.” In this testing process, nucleic acid extraction serves as the first critical step that determines the efficiency and accuracy of subsequent tests.

Traditional extraction methods are facing three major challenges

First is speed. When dealing with large volumes of outpatient samples, manual processes or outdated extraction methods can no longer keep up with the“test as soon as samples arrive”pace. Second is accuracy. A positive screening result does not equate to a confirmed diagnosis, but the risk of missed cases due to false negatives is magnified in large-scale testing scenarios. Third is cost. When the volume of tests jumps from the thousands to the tens of thousands, the extraction cost per sample directly determines the laboratory’s operational efficiency.

The Magnetic Bead-Based Viral DNA/RNA Extraction Kit is a solution specifically designed for this new application.

Shanghai Lingjun Biotechnology’s magnetic bead-based viral DNA/RNA extraction kit utilizes surface-modified nanoscale magnetic beads to enable the specific adsorption and efficient elution of nucleic acids.

This product can be used for the extraction, enrichissement, and purification of nucleic acids from samples containing viruses and pathogens (such as tissue, cellules cultivées, blood spots, swab washings, viral preservation solutions, échantillons environnementaux, salive, sperme, urine, and lymph).

Product Case Studies：Three replicate amplification curves for classical swine fever virus from serum samples extracted using test kits from the same batch

Compared to traditional column-based methods or the phenol-chloroform method, its advantages are particularly evident in batch testing scenarios：

Haut débit, compatible with automation.

The magnetic bead method is naturally suited for automated workstations; the 96-well plate format increases the processing capacity per batch from dozens to hundreds of samples, perfectly aligning with the pace of bulk screening in outpatient settings.

Higher purity and fewer residual inhibitors.

The magnetic bead method provides a more thorough washing process, resulting in higher-purity nucleic acids after elution, which directly reduces the risk of inhibition in subsequent detection methods such as PCR and lowers the re-testing rate.

Simpler to operate, with lower staff training costs.

The magnetic bead method features consistent procedures that are easy to standardize, thereby reducing human error. It also significantly shortens the training period for new lab personnel needed to handle the surge in testing volume.

Résumé

When “testing every blood sample” has evolved from a policy into routine laboratory practice, the bottleneck in testing capacity is no longer just instrument throughput, but also the speed and stability of each step in sample preparation. The magnetic bead-based nucleic acid extraction kit addresses precisely this efficiency issue at the very beginning of the process.

If your lab is facing the pressure of a doubling sample volume or is planning a new nucleic acid testing workflow, you might want to start by reevaluating the extraction step—because no matter how accurate the subsequent testing may be, it all depends on a high-quality nucleic acid template.

Fournisseur

Société de biotechnologie Shanghai Lingjun., Ltd.a été établi en 2016 qui est un fabricant professionnel de matériaux biomagnétiques et de réactifs d'extraction d'acide nucléique.

Nous avons une riche expérience dans l'extraction et la purification des acides nucléiques, purification des protéines, séparation cellulaire, chimiluminescence, et autres domaines techniques.

Nos produits sont largement utilisés dans de nombreux domaines, comme les tests médicaux, tests génétiques, recherche universitaire, sélection génétique, et ainsi de suite. Nous fournissons non seulement des produits, mais pouvons également entreprendre des OEM, ODM, et autres besoins. Si vous avez un besoin connexe, n'hésitez pas à nous contacter .