Silicon-based Magnetic Beads

Introduction

SiO₂ beads are magnetic microspheres with a layer of silicon dioxide (SiO₂) on the surface, thus exposing a large number of silicone hydroxyl groups (-Si-OH) on the surface.

Characteristics

High specificity and purity: this is its greatest advantage. In the presence of leaving liquid salts, the specificity of adsorption of nucleic acids by silica hydroxyl groups is much higher than the adsorption of impurities such as proteins and sugars. Combined with effective cleaning (ethanol is commonly used), extremely pure nucleic acids can be obtained, which is ideal for downstream sensitive applications (e.g. PCR, sequencing).

Efficient and reliable: high efficiency and quality recovery for nucleic acid extraction from all types of samples (blood, tissue, cells, plants, bacteria, etc.).

Automation-friendly: the whole process (binding-washing-elution) is simple and straightforward, making it extremely easy to automate high-throughput operations.

Biocompatible: Silica surfaces are hydrophilic, which is "gentler" than hydrophobic surfaces and helps to reduce non-specific adsorption of certain biomolecules.

Application

Genomic DNA extraction: High-quality genomic DNA is extracted from a variety of biological samples.

Viral RNA/DNA extraction: e.g. HPV, HIV, HCV viruses as well as the new coronavirus (SARS-CoV-2) nucleic acid detection, the majority of extraction kits are based on this principle.

Plasmid DNA extraction、Total RNA extraction、Trace amounts of DNA are extracted from ancient samples such as fossils and trace and highly degraded samples (e.g., blood, hair)

Supplier Introduction

Shanghai Lingjun Biotechnology Co., Ltd. was established in 2016 and is a professional manufacturer of biomagnetic materials and nucleic acid extraction kits.

We have rich experience in nucleic acid extraction and purification, protein purification, cell separation, chemiluminescence and other technical fields.

Our products are widely used in many fields, such as medical testing, genetic testing, university research, genetic breeding, and so on. We not only provide products but also can undertake OEM, ODM, and other needs. If you have related needs, please feel free to contact us sales01@lingjunbio.com.

Payment Methods

L/C, T/T, Western Union, Paypal, Credit Card etc.

Shipment

By sea, by air, by express as soon as possible once payment receipt.

FAQs

Q: How to avoid nucleic acid degradation when using Silicon-based Magnetic Beads for nucleic acid extraction?
A: During the nucleic acid extraction process, RNase-free kits and consumables should be used and operated at low temperatures to reduce nuclease activity and prevent nucleic acid degradation.

Q: Can Silicon-based Magnetic Beads be reused?
A: This depends on the design and application of the magnetic beads. Some magnetic beads can be reused after proper cleaning and regeneration, but repeated use may cause the performance of the beads to degrade.

Q: How to choose suitable Silicon-based Magnetic Beads?
A: The characteristics of the target molecule, experimental conditions, and expected purification efficiency should be considered when selecting magnetic beads. It is recommended to consult a professional supplier to select the best type of magnetic beads based on the specific application.

As an important tool in modern life science research, silicon-based magnetic beads are constantly promoting the advancement of scientific research and clinical technology with their excellent performance and wide applicability. Whether it is basic research or clinical application, silicon-based magnetic beads have shown irreplaceable value. If you have more in-depth needs or questions about silicon-based magnetic beads, please feel free to contact us and we will serve you wholeheartedly.