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温泉からDNA鑑定まで

の夏に 1966, ハドソン・フリッツ, インディアナ大学の学部生, イエローストーン国立公園の端にある小屋に移動した. 彼はその後、微生物学者のトーマス・ブロックの下で働いていました。.

Brooke was convinced that certain microorganisms could survive in temperatures far exceeding expectations. その結果, Fritz made daily trips to the hot spring area to collect bacterial samples. 9月に 19 of that year, he successfully cultured a pale yellow microbial sample from the Mushroom Hot Spring. Under the microscope, he observed abundant cells collected from water near boiling point.

形 1: A corner of Yellowstone National Park in the United States

I saw something my predecessors had never seen,” recalls Fritz, now at the Sandford Burnham Prebises Institute for Medical Discovery in California. “To this day, the sight of that microscope image still sends shivers down my spine.

Three years later, Fritz and Brock described one of these bacteria, naming itThermophilus aquaticus.This bacterium thrives optimally at 70°C. で 1976, a team from the University of Cincinnati, Ohio, isolated an enzyme from Thermophilus aquaticus—aDNA polymerasecapable of synthesizing new deoxyribonucleic acid (DNA) at 80°C.

Seven years later, a substance dubbed “Taq ポリメラーゼ” proved ideal for biochemist Kary Mullis to develop the polymerase chain reaction (PCR) technique, which can rapidly amplify a single DNA fragment into thousands of copies. Since Mullis required high temperatures to denature DNA strands, he needed a polymerase capable of functioning at elevated temperatures.

今日, PCR technology has become an indispensable tool, widely applied across multiple fields. 医療分野では, it is used for organ transplant matching and cancer diagnosis; in criminal investigation, it enables DNA fingerprint identification. の PCR amplification reagents developed by Shanghai Lingjun Biotechnology are also extensively used in teaching experiments, earning high praise from both teachers and students.

Shanghai Lingjun Bio PCR Amplification Kit

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上海霊軍生物技術有限公司, 株式会社に設立されました 2016 生体磁性材料と核酸抽出試薬の専門メーカーです.

核酸抽出・精製の経験が豊富です。, タンパク質の精製, 細胞分離, 化学発光, その他の技術分野.

当社の製品はさまざまな分野で広く使用されています, 医療検査など, 遺伝子検査, 大学の研究, 遺伝子育種, 等々. 製品のご提供だけでなくOEMも承ります, ODM, その他のニーズ. 関連するニーズがある場合, お気軽にお問い合わせください .

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