마그네틱 비드 기반 핵산 추출 기술: 바이오의약품 산업의 효율성 혁명을 선도합니다.

In the current era of surging demands for precision medicine and large-scale disease screening, a key technology is quietly driving the efficiency revolution in the biopharmaceutical industry – 자기 비드 기반 핵산 추출. With its significant advantages of high efficiency, 오토메이션, 순도가 높고, this technology has rapidly become an indispensable core tool in molecular diagnostics, 유전자 서열 분석, and new drug development fields.

Using our serum/plasma virus nucleic acid extraction reagents, HBV national standard gradient diluents were extracted on the automatic nucleic acid extraction and purification instrument LJbio32H. The extracted products of each concentration gradient diluent were detected by HBV-qPCR, with a correlation coefficient R>0.99. The specific data is as follows:

결과 분석：The accuracy of the reagent is very high, and the sensitivity is still good when extracting low concentration samples.

Compared with the traditional centrifugal column method, magnetic bead-based extraction achieves rapid separation and purification through the specific binding of nucleic acids to surface-modified magnetic particles under the action of an external magnetic field. This principle enables breakthroughs in throughput, 속도, and consistency. 최근에는, this technology has excelled in scenarios such as large-scale screening of infectious diseases (such as COVID-19 nucleic acid testing), tumor liquid biopsy (microscopic ctDNA capture), and genetic disease analysis, effectively supporting high-throughput, standardized modern testing requirements.

미량의 인간 Hela 세포에서 샘플로 핵산을 추출했습니다., 5 세포, 10 세포, 20 세포, 500 세포가 추출되었습니다, 그리고 얻은 핵산은 Agilent를 사용하여 분석되었습니다. 4200 핵산 단편 분포, 그리고 얻은 결과는 아래와 같습니다: 

1. 애질런트의 전기영동도 4200 고감도 RNA 스크린테이프 분석

D1: 50 헬라 세포G1: 20 헬라 세포지하 2층: 10 헬라 세포E2: 5 헬라 세포

2. 피크 다이어그램 50/20/10/5 Hela 세포 추출

• 피크 다이어그램 5 Hela 세포 추출

• . Qubit의 테스트 결과

아니요.	샘플 섭취	생산하다(의/μL)
1	50 헬라 세포	0.242
2	20 헬라 세포	0.136
3	10 헬라 세포	0.112
4	5 헬라 세포	0.096

결과 분석： 애질런트 4200 전기영동 결과를 볼 수 있습니다.: 5– 인간 Hela 세포 샘플 50개 흔적, 핵산 단편으로 얻을 수 있다, 추출산물은 18s RNA였다., 28sRNA, DNA가 800bp 이상인 경우.

The wave of industry innovation continues to surge. Domestic leading enterprises have launched fully automated solutions integrating magnetic bead extraction, 달성 “sample input and result output” in closed tubes, reducing extraction time to minutes and significantly enhancing emergency testing capabilities. 동시에, breakthroughs in domestic high-end magnetic bead raw materials, such as those from companies like Shanghai Lingjun Biotechnology, have broken the import monopoly, reducing the cost of a single sample by over 30%, significantly enhancing the autonomy of the industrial chain. Capital markets have shown great favor for this sector, with many related enterprises completing large-scale financing recently, driving technological iteration into a fast lane.

미래를 바라보며, with the explosion of personalized medical care and immediate testing (POCT) demands, magnetic bead-based technology is evolving towards higher sensitivity, better anti-interference performance, and green biodegradability. Its combination with microfluidics and artificial intelligence is expected to give rise to a new generation of intelligent extraction platforms, continuously providing key infrastructure for the innovation and development of the biopharmaceutical industry.

공급자

상하이 링쥔 생명공학 유한회사, 주식회사에 설립되었습니다 2016 생체자성재료 및 핵산추출시약 전문제조업체입니다..

핵산 추출 및 정제 분야에서 풍부한 경험을 보유하고 있습니다., 단백질 정제, 세포 분리, 화학발광, 및 기타 기술 분야.

우리의 제품은 많은 분야에서 널리 사용됩니다., 의료 테스트와 같은, 유전자 검사, 대학 연구, 유전자 육종, 등. 우리는 제품을 제공할 뿐만 아니라 OEM도 수행할 수 있습니다., ODM, 그리고 다른 필요. 관련된 필요사항이 있는 경우, 저희에게 연락하게 자유롭게 느끼십시오 .